In Yu-Gi-Oh! Reshef of Destruction, the player returns to Battle City and embarks on a mission to retrieve stolen millennium cards that threaten the world. The goal is to stop an evil entity known as Reshef from drowning the world in darkness. To do this, players must build a powerful deck out of 800 available cards (including all three Egyptian god cards). With this deck they can face their enemies in strategic card battles and ultimately save the world from destruction.