In BloodRayne 2, players take on the role of dhampir BloodRayne as they battle against their evil vampire siblings in an effort to prevent them from creating a new era of vampire supremacy. Players can perform acrobatic actions and fighting combos with access to twelve finishing moves. The more creative kills you make, the more you can upgrade your weapons and abilities. You also have access to a powerful Blood Rage feature when your Bloodlust meter is full. With these powers at your disposal, you must use strategy and skill to help protect humanity from becoming mere cattle for the bloodthirsty predators that hunt them.

BloodRayne: Betrayal is a 2D side-scrolling action game that follows the story of BloodRayne, a half-vampire warrior. In this game, BloodRayne is joined by a new ally to fight against an evil group of vampires who are plotting something sinister. The player will take control of both characters and use their special abilities in order to defeat enemies and progress through levels. Players must also solve puzzles and make strategic decisions as they battle their way towards victory.