Mega Man ZX is a video game in which players assume the role of either Vent, a human male character, or Aile, his female counterpart. They are employees of the Girouette Express courier service and are tasked with transporting a package containing Model X and Model Z Biometals when they are attacked by mysterious Mavericks who seek to take them for themselves. During the attack, Model X Biometal fuses with Vent/Aile while Model Z Biometal fuses with their boss Girouette. With newfound power at their disposal from combining both substances into one called "Model ZX," Vent/Aile must discover who the enemies are and what they intend to do with it before it's too late.

Mega Man ZX Advent is an action-packed game for the Nintendo DS. Players follow two heroes, Grey and Ashe, as they search for answers to a chaotic war between humans and robots. With the dynamic Biometal system at its core, players can switch back and forth between forms including eight bosses with unique abilities. The game offers various ways of fighting bosses in order to win rewards such as nearly 24 different items. It also features co-op or head-to-head wireless play (two cartridges required) as well as a downloadable mini game (one cartridge required).